Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells
نویسندگان
چکیده
منابع مشابه
Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells.
PURPOSE Clonal evolution of cancer may be regulated by determinants of stemness, specifically self-renewal, and current therapies have not considered how genetic perturbations or properties of stemness affect such functional processes. Glioblastoma-initiating cells (GICs), identified by expression of the cell surface marker CD133, are shown to be chemoradioresistant. In the current study, we so...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2015
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-14-3147